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کیس شماره چهار: نفروپاتولوژی

1404/06/16 | 09:34

A 16-year-old male without any systemic disease went to the doctor's office to complain of occasional headaches, which started 6 months ago.

His blood pressure was 150/90.

 Laboratory results are as follow:WBC: 13400/L,Hemoglobin: 10.5mg/dl,Platelets: 243000/L,Blood Urea Nitrogen: 185,Creatinine: 2.9 mg/dL

Urine analysis: protein 3+, blood: 3+, RBC: 16-18 /LPF, granular cast: 2-3/LPF,24 h urine volume: 1400cc, 24 h Creatinine: 590 mg, 24 h protein: 998 mg, weight: 58 kgIn secondary work-up, he had a normal level of Complements.

FH: his mother and aunt’s have history of proteinuria and hematuria. They didn't have been evaluated

Microscopic scans:

 

                                                                                                                                         

 

Immunofluorescence study for IgG, IgA, IgM, C3c,C4c, C1q, and Albumin show No glomerular or tubular staining.

Fibrinogen highlighted cellular crescents.

 

Electron microscopy:

                                                   

 

 

What is your diagnosis?

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